EXHAUSTED
* You are slowed.
* You are weakened.
* You can’t flank an enemy.

This condition serves as a good paragon-tier condition extension of both slowed and weakened (and even prone for that matter). This is helpful for the poison creation rules. For example, spider poisons generally cause the weakened condition (Strength damage in 3e). That’s great for a heroic-tier spider poison. When I’m creating a paragon- or epic-tier spider poison, I don’t want it to just cause the weakened condition, which is too weak for those levels.

MUTED
* You can’t speak.
* You take a -5 penalty to skill checks that require the target to hear you, e.g., Diplomacy, Intimidate, etc.
* You can’t use powers that require the target to hear you, e.g., the ranger’s skilled companion power, the warlord’s Combat Leader class feature, etc.

This is an obvious addition to the blinded/deafened set, and I think it might actually have some interesting implications at the game table. Heroic tier.

NAUSEATED
* You are slowed.
* You can’t take standard actions.
* You can’t attack.
* You take a -2 penalty to all defenses.

This is the one I’m most hesitant about. Principally, I created it for thematic reasons. Stunned, weakened, etc. are viable substitutions for a sickening effect, but they don’t work thematically. Additionally, I wanted another solid paragon-tier condition. (Paragon-tier conditions are helpful because they easily serve all three tiers, i.e., potent heroic-tier poisons, average paragon-tier poisons, and weaker epic-tier poisons.)

Wheezing: It takes the character two healing surges in order to get one surge’s effect. Surges granted by another player count as one of the two. All characters have combat advantage over you. Effect lasts until save is made.